platelet derived growth factor!

platelet derived growth factor

Comprehensive Analysis

1) "Platelet" -- As to platelet derived growth factor plate·let Pronunciation: 'plAt-l&t Function: noun : a minute flattened body (as of ice or a mineral); especially : a minute colorless disklike body of mammalian blood that assists in blood clotting by adhering to other platelets and to damaged epithelium -- called also blood platelet, thrombocyte Pronunciation Symbols A 250 ml bag of newly collected platelets. Thrombocytes Platelets or thrombocytes are the cell fragments circulating in the blood that are involved in the cellular mechanisms of primary hemostasis leading to the formation of blood clots. Dysfunction or low levels of platelets predisposes to bleeding, while high levels, although usually asymptomatic, may increase the risk of thrombosis. 1 Anatomy 2 Physiology 2.1 Production 2.2 Circulation 2.3 Function 2.4 Activators 2.5 Inhibitors 2.6 Drugs that inhibit platelet function 3 Role in disease 3.1 High and low counts 3.2 Diseases 4 Discovery 5 Additional images 6 References 7 See also Like red blood cells, platelets are anuclear (no cell nucleus) and discoid (disc shaped); they measure 1.5–3.0 μm in diameter. The body has a very limited reserve of platelets, so they can be rapidly depleted. They contain RNA, a canalicular system, and several different types of granules; lysosomes (containing acid hydrolases), dense bodies (containing ADP, ATP serotonin and calcium) and alpha granules (containing fibrinogen, factor V, vitronectin, thrombospondin and von Willebrand factor), the contents of which are released upon activation of the platelet. A scanning electron microscope (SEM) image of normal circulating human blood. One can see red blood cells, several knobby white blood cells including lymphocytes, a monocyte, a neutrophil, and many small disc-shaped platelets. Platelets are produced in the bone marrow; the progenitor cell for platelets is the megakaryocyte. It is about twelve times larger than an er..." 2) "Derived" -- As to platelet derived growth factor de·rive Pronunciation: di-'rIv, dE- Function: verb Inflected Form(s): de·rived; de·riv·ing Etymology: Middle English, from Anglo-French deriver, from Latin derivare, literally, to draw off (water), from de- + rivus stream -- more at RUN transitive verb 1 a : to take, receive, or obtain especially from a specified source b : to obtain (a chemical substance) actually or theoretically from a parent substance 2 : INFER, DEDUCE 3 archaic : BRING 4 : to trace the derivation of intransitive verb : to have or take origin : come as a derivative synonym see SPRING - de·riv·er noun Pronunciation Symbols In phylogenetics, derived members of a group diverged after another member (or subgroup of members) had already diverged. The earlier members are termed basal. Neither word means anything on its own, and each can only be interpreted in the context of other members of the group. For example: Monocots and eudicots are derived flowering plants, having diverged from each other after palaeodicots had already split from the line. A subgroup of great apes containing chimpanzees and gorillas is derived relative to the orangutan, which diverged earliest. For the sake of precision, biologists often prefer "derived" over "advanced," a term which may inaccurately imply superiority. Although a derived member of a group may have higher fitness in a given environment, this is not always the case. It is quite common for both basal and derived members of a group to exist simultaneously and be well-suited for different ecological niches, or the same niche in different locations. ..." 3) "Growth" -- As to platelet derived growth factor growth Pronunciation: 'grOth Function: noun 1 a (1) : a stage in the process of growing : SIZE (2) : full growth b : the process of growing c : progressive development : EVOLUTION d : INCREASE, EXPANSION <the growth of the oil industry> 2 a : something that grows or has grown b : an abnormal proliferation of tissue (as a tumor) c : OUTGROWTH d : the result of growth : PRODUCT 3 : a producing especially by growing <fruits of his own growth> 4 : anticipated progressive growth especially in capital value and income <some investors prefer growth to immediate income> Pronunciation Symbols Growth can mean increase in spatial number or complexity for concrete entities in time or increase in some other dimension for abstract or hard-to-measure entities. It can also refer to the mode of growth, i.e. how growth parameters themselves vary with time: Cell growth Individual growth Fungal growth Auxology (Human development) Human development (biology) Growth "spurt" (rapid change in puberty) Human development (psychology) Population growth Bacterial growth Tumours can sometimes be referred to as a growth Growth hormone Economic growth For financial growth due to simple interest or compound interest see Interest Personal growth, i.e., Personal development Mode Logistic growth Exponential growth ..." 4) "Factor" -- As to platelet derived growth factor 1fac·tor Pronunciation: 'fak-t&r Function: noun Etymology: Middle English, from Middle French facteur, from Latin factor doer, from facere 1 : one who acts or transacts business for another: as a : BROKER 1b b : one that lends money to producers and dealers (as on the security of accounts receivable) 2 a (1) : one that actively contributes to the production of a result : INGREDIENT <price wasn't a factor in the decision> (2) : a substance that functions in or promotes the function of a particular physiological process or bodily system b : a good or service used in the process of production 3 : GENE 4 a : any of the numbers or symbols in mathematics that when multiplied together form a product; also : a number or symbol that divides another number or symbol b : a quantity by which a given quantity is multiplied or divided in order to indicate a difference in measurement <costs increased by a factor of 10> - fac·tor·ship /-"ship/ noun Pronunciation Symbols A factor, a Latin word meaning 'who/which acts' may refer to: Factor (agent), a person who acts for another, notably a mercantile and/or colonial agent Factor (Scotland), a person or firm managing a Scottish estate Factors of production, resources used in the production of goods and services Factoring (finance), an entity which advances finance against receivable Max Factor, a cosmetics firm Max Factor, Sr., a Polish-American businessman and cosmetician who founded the Max Factor Cosmetics Company John Factor, a Prohibition-era gangster In science: An enzyme, proteins that catalyze chemical reactions Coagulation factors, substances essential for blood coagulation A phenomenon presumed to affect an experiment; see design of experiments In mathematics: Factorization the decomposition of an object into a product of other objects Integer factorization, the process of breaking down a composite number into smaller non-trivial divisors a coefficient a divisor of a particular number a von Neumann algebra with a trivial center In technology: Factor (programming language), a dynamically typed concatenative programming language Authentication factor, a piece of information used to verify a person's identity for security purposes Human factors, a profession that focuses on how people interact with products, tools, or procedures "Functionality, Application domain, Conditions, Technology, Objects and Responsibility;", In object-oriented programming ..." 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